منابع مشابه
Bradycardia-dependent long QT syndrome, sudden death and late potentials.
The report by Tobe et al. (1) in this issue of the Journal about late potentials in patients with familial long QT syndrome offers a suggestion that the signal-averaged electrocardiogram (ECG) may be a useful diagnostic tool in the detection and risk stratification of patients with QT prolongation. The association between long QT syndrome and late potentials, a marker of structural substrate fo...
متن کاملCompound mutations: a common cause of severe long-QT syndrome.
BACKGROUND Long QT syndrome (LQTS) predisposes affected individuals to sudden death from cardiac arrhythmias. Although most LQTS individuals do not have cardiac events, significant phenotypic variability exists within families. Probands can be very symptomatic. The mechanism of this phenotypic variability is not understood. METHODS AND RESULTS Genetic analyses of KVLQT1, HERG, KCNE1, KCNE2, a...
متن کاملLong QT Syndrome
Background. Erythromycin is known to prolong ventricular repolarization and has been associated with the occurrence of torsades de pointes. In this study, we have investigated potential mechanisms in vivo and in vitro for induction of an acquired long QT syndrome by erythromycin. Methods and Results. Ventricular electrograms and endocardial monophasic action potentials were recorded in anesthet...
متن کاملThe Long QT Syndrome
Introduction The Long QT syndrome (LQTS) can be inherited or acquired and is of particular interest and concern at present. Patients with LQTS are predisposed to the ventricular tachyarrhythmia torsade de pointes (TdP) which causes syncope and sudden death. Inherited LQTS is the prototype of the "primary cardiac arrhythmias" or "cardiac ion channelopathies". The study of inherited LQTS has prov...
متن کاملLong Qt Syndrome
Department of Biology, National Taiwan Normal University, Taipei; Department of Internal Medicine, Chang Gung Memorial Hospital and Chang Gung University, Taipei; Department of Internal Medicine, Wei Gong Memorial Hospital, Tou Fen, Miaoli; Division of Cardiology, Department of Medicine, Veterans General Hospital-Taipei; and Department of Medical Research and Education, Veterans General Hospita...
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ژورنال
عنوان ژورنال: Annals of Noninvasive Electrocardiology
سال: 2017
ISSN: 1082-720X
DOI: 10.1111/anec.12517